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doi:10.1093/oxfordjournals.aje.a114824 ^ Williams C.M., Burdge G

Therefore, the relatively low abundance of lipoylation in untreated cells suggests that lipoylation is rate-limiting for the OGDHc, and our findings are consistent with the accumulation of Lp glu following ABHD11 inhibition, which reduces OGDHc activity (Fig

The 0.01 mg/kg dose that showed consistent effects in rats translates to approximately 0.0016 to 0.004 mg/kg in humans, which works out to roughly 0.112 to 0.28 mg for a 154-pound person

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