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Acquired resistance mechanisms to combination met-TKI/EGFR-TKI exposure in met-amplified EGFR-TKI resistant lung adenocarcinoma harboring an activating EGFR mutation

[DOI] [PMC free article] [PubMed] [Google Scholar] [13].Stathopoulou C, Nikoleri D, Bertsias G

Histological findings from both animal models and human studies have described sinusoidal dilatation, microvesicular steatosis, and pericentral necrosis, changes commonly associated with oxidative and inflammatory stress

Conversely, miR-302a-3p inhibitors blocked ferroptosis induced by erastin or RSL3

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This structure probably enables the reaction with more complex lipid hydroperoxides, but this has been proven only for GPx4 [132]