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As the core effector molecule of this pathway, GPX4 is a unique selenoprotein and the only member of the GPX family capable of directly catalyzing the reduction of membrane phospholipid hydroperoxides (30)

High LDL levels contribute to fat accumulation in the arteries (atherosclerosis), significantly increasing the risk of heart attacks and strokes

Both the participants in the Minguez-Alarcon et al

EG-Se/Pt can induce abnormal increases in ROS by depletion of glutathione

For example, combining GPS with nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce NSAID-induced gastrointestinal toxicity through GPSs anti-inflammatory and gastroprotective effects (Yang et al., 2018)

Glutathione also regenerates vitamin C, restoring its antioxidant power