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[DOI] [PMC free article] [PubMed] [Google Scholar] 8.Chiesi M, Huppertz C, Hofbauer KG

When patients treated with oral levodopa and LCIG were compared, there was a significant difference in -diversity between groups and higher abundance of genera Escherichia and Serratia in LCIG patients [63]

When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)

DSIP is not an approved medicine

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2.8 Altered iron metabolism Iron accumulation is reportedly a mechanism that can lead to cellular damage in both neurodegeneration and metabolic dysfunction models, and iron-dependent programmed cell death (ferroptosis) is observed in both conditions (Du et al., 2024)