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Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome

One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits

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Remote Therapeutic Monitoring Unlike Remote Physiologic Monitoring (RPM), which measures a physiological parameter, such as heart rate, weight and glucose levels, Remote Therapeutic Monitoring (RTM) reviews data related to therapeutic responses, including signs, symptoms, and functions