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For Pf AMA1 (1Z40), furans: Nitrofurantoin, Prazosin, Furosemide, Ranitidine( n = 4) and pyrazoles: Rimonabant, Celecoxib, Ruxolitinib, Pyrazofurin ( n = 4) were used as reference inhibtors

Dihexa works by binding to the HGF receptor c-Met on hippocampal neurons, activating intracellular signaling pathways that increase synaptogenesis, dendritic spine density, and NMDA receptor expression

Most longevity peptides target one or two biological pathways

Mechanism Investigation: Examine whether acetylation affects upstream signaling pathways differently than unmodified form

158 Drug screening Drug screening can be categorized into two primary approaches: target-based screening and phenotypic screening

N., Prasad, P