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negevensis encodes a virus tegument-like DUB, Josephin-like DUBs and ULPs, of which one enzyme even reacts with an activity-based probe of ISG15 26,27,28,29

The endogenous antioxidant defense system, such as Nrf2 and CD44v9, may act coordinately to neutralize ROS, and protect cells against the biological damage of ROS-induced oxidative stress

EMBO J 26:559566 Ray PD, Huang BW, Tsuji Y (2012) Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

Mustapha MT

Changes in the availability of GSH are likely to influence in a negative fashion the function of the immune system and of the antioxidant defense mechanisms

10.1074/jbc.m610737200 53 FinnA