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In one study, rats were fed a diet high in fat and ethanol to create an oxidized cellular environment, in which 4-hydroxynonenal (4-HNE) was used as a marker to identify modified proteins
666 Ultra-high performance liquid chromatography-mass spectrometry analysis showed that moderately controlled cortical impact induces significant expression of PUFA in mouse serum, leading to lipid peroxidation and ferroptosis
2000;197(Pt 4):575585
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