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Concentrations of butyrate greater than 5-8 millimoles are known to induce apoptosis [32]

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The use of HPLC with electrochemical detection can overcome these problems by direct measurement of GSH and GSSG [39,40] but can be very expensive

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This review provides a comprehensive summary of the pathological mechanisms of IUA, with a particular focus on fibrosis, immune dysregulation, and EMT (Figure 1)
