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As pointed out [60], it has to be the counteraction of the reduced capillary perfusion pressure, increased cerebral blood volume, venous flow obstruction, increased intracranial pressure and blood-brain barrier disruption, resulting in a decreased cerebral blood flow [60]

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3-7 ), grossly, clinically, microscopically, and in particular, biomechanically, and they could sustain without leaking only a very small volume ( Fig

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