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Description
The secondary mechanism is passive diffusion: approximately 1% of any oral B12 dose is absorbed by passive diffusion across the intestinal lining, independent of intrinsic factor and without saturation
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The two strategies act on different points in the same pathway and have distinct mechanistic and pharmacological profiles in the published research
doi:10.7326/M19-0830
Walter Kolch, [email protected] These authors share senior authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
