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In streptozotocin (STZ)-induced diabetic rats, ALA (100 mg/kg orally) demonstrated superior peripheral nerve protection compared to insulin, improving nerve conduction velocity (NCV) and promoting regeneration, even under persistent hyperglycemia [98]

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The major pathological hallmarks of PD are represented by the progressive loss of dopamine(DA)-ergic neurons in the substantia nigra (SN) of the central nervous system (CNS) associated with cytoplasmic inclusions termed as Lewy bodies and Lewy neurites (Spillantini et al., 1997)

It may also help manage symptoms related to autoimmune disorders by reducing chronic inflammation and oxidative stress

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