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Elevated NNMT activity has been associated with increased fat accumulation, reduced metabolic efficiency, and impaired cellular energy production

[11] Medical uses [edit] Vitamin B 12 deficiency Standard therapy for treatment of vitamin B 12 deficiency has been intramuscular (IM) or intravenous (IV) injections of hydroxocobalamin (OHCbl), since the majority of cases are due to malabsorption by the enteral route (gut)