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Description
Figure 1 was designed by EI, KK, and VC
Data analysis, including gating, quantification, and generation of density plots/histograms, was performed using the NovoFast program (Agilent Technologies, USA)
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Amino acid metabolism in health and disease
*Correspondence: Xiangwei Chang, [email protected]
Furthermore, elevated cytosolic aconitase (c-ACNT) and isocitrate dehydrogenase (ICD2), synergistically enhanced by iron accumulation, drive citrate flux toward NADPH and -KG generation, thereby exacerbating intracellular citrate depletion
