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Description
Panieri E, Saso L

Summarizing the role of ferroptosis in cardiovascular diseases could pave the way for innovative clinical treatments targeting ferroptosis

Glutathione uptake assay in immunopurified mitochondria Mitochondria were purified from HEK-293T cells expressing 3xHA-OMP25-mCherry (mitochondrial isolation) or 3xMyc-OMP25-mCherry (background control) according to a previously described protocol 40

This ratio of GSH: GSSG is maintained by the action of GSSG reductase, which requires NADPH+ as the reducing cofactor

[DOI] [PubMed] [Google Scholar] 266.Keck MV, Lippard SJ
doi: 10.1016/j.freeradbiomed.2006.02.024