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The most compelling candidates address multiple mechanisms simultaneously, which is why they show stronger results than compounds targeting a single pathway

Int J Hematol 54: 295298, 1991 [PubMed] [Google Scholar] 75.Nichols KD, Kirby GM

S.AndreouE.AphamisG.PantzarisM.IoannouM.PatrikiosI

It works through a unique mechanism involving the activation of two different types of receptors in the body: the glucagon-like peptide-1 (GLP-1) receptor and the glucose-dependent insulinotropic polypeptide (GIP) receptor

Hence, clarifying the mechanism of necroptosis in pathological processes is particularly important for the prevention and treatment of various diseases

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