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Chemical synthesis using solid-phase peptide synthesis (SPPS) is suitable for shorter peptides and allows for precise control over peptide structure

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These compounds have been shown to reduce the levels of pro-inflammatory cytokines (TNF-, IL-, and IL-12), inhibit NF-B p65 and IB phosphorylation, as well as modulate the TLR4 and TLR4-related pathways (NF-B and MAPK) in vitro and in vivo [237]

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Uptake of materials from the nasal cavity into the blood and brain: are we finally beginning to understand these processes at the molecular level