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These include replicative exhaustion due to telomere shortening, DNA damage, oncogene activation, mitochondrial dysfunction, metabolic stress, proteotoxic stress, and exposure to certain inflammatory mediators or mitogens [49]

PMID: 16342165

10.1093/toxsci/kfq227 116 Pogrmic-MajkicK.KaisarevicS.FaS.DakicV.GlisicB.HrubikJ.et al (2012)

Furthermore, ~70% of individuals with T2D are concurrently diagnosed with metabolic dysfunction-associated steatotic liver disease (MASLD)
