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Despite these results, the development of AOD-9604 stopped in 2007

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It has even been proposed that NNMT be considered as a novel and sensitive serum biomarker for detecting colorectal cancer, outperforming the clinical significance of carcinoembryonic antigen (CEA) (42)

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We divided the cohort based on the aforementioned criteria into controllers ( n = 6) and noncontrollers ( n = 10)