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Abstract Mitochondrial dysfunction and oxidative damage are highly involved in the pathogenesis of Parkinsons disease (PD)

The combination of vancomycin, neomycin sulfate, metronidazole, ampicillin, and other broad-spectrum antibiotics can alleviate choline-induced atherosclerosis in mice, and the mechanism may be related to the inhibition of choline conversion to TMA, the reduction of TMAO levels, and the inhibition of macrophage foaming

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They adopted the following exclusion criteria: pregnancy, women with suspected pregnancy or breastfeeding