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However, the net effect depends on overall biological context, regulatory mechanisms, and timing

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Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models

As NOX complexes assemble within cell receptor or lipid rafts, the resultant radicals act on nearby targets before dismutation or clearance, enabling precise, spatially confined signaling with limited duration [22]

Traboulsi H, Cherian M, Rjeili MA, Preteroti M, Bourbeau J, Smith BM, Eidelman DH, Baglole CJ (2020) Inhalation toxicology of vaping products and implications for pulmonary health