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10.1016/j.biopha.2021.111729 17 HiraS.SaleemU.AnwarF.RazaZ.RehmanA

G., Mann, T

NAD + is involved in the catabolism of glucose in glycolysis, resulting in the production of ATP

[2] Hydroxocobalamin is administered via intramuscular or intravenous injection to treat and prevent vitamin B deficiency, particularly in conditions like pernicious anemia where oral B absorption is impaired

If you have been taking methylfolate, methylcobalamin, and P5P in the right forms and doses for three months and the symptom has not improved, the symptom is probably not being driven by MTHFR