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Total synthesis and comparative analysis of orlistat, valilactone, and a transposed orlistat derivative: inhibitors of fatty acid synthase

219 , e201907099 (2020)

Braissant O, Honegger P, Loup M, Iwase K, Takiguchi M, Bachmann C (1999) Hyperammonemia: regulation of argininosuccinate synthetase and argininosuccinate lyase genes in aggregating cell cultures of fetal rat brain

These findings should be viewed as hypothesis-generating , providing a systems-level context for the observed metabolite changes rather than evidence of causal normalization

Gordts PL, Nock R, Son NH, Ramms B, Lew I, Gonzales JC, Thacker BE, Basu D, Lee RG, Mullick AE, Graham MJ, Goldberg IJ, Crooke RM, Witztum JL, Esko JD (2016) ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors

Among these, XPO-1, highly conserved exportin, ranked 14th with a 9.59-fold enrichment ( p = 0.0044), and its binding partner RAN-1 showed a 3.56-fold enrichment ( p = 0.0599) (Fig