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Scalable production of extracellular vesicles and its therapeutic values: a review

Marciano, Y., Nayeem, N., Dave, D., Ulijn, R

In AD, NAC elevates GSH levels to sustain GPX4 activity, thereby reducing lipid peroxidation accumulation and inhibiting key ferroptosis pathways for neuroprotection (188)

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These findings suggest that NAC should be used at a dose 1200 mg/day to prevent exacerbations in patients with a chronic bronchitis phenotype of COPD and airway obstruction, while regular doses (600 mg/day) may be sufficient in the absence of airway obstruction [37]