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So, lets go beyond the simple 'yes' and explore precisely why refrigeration for a compound like Lipo C isn't just a suggestion

10.1155/2019/9372182 129 RodrguezL

Primary concerns include increased injection site reactions from multiple subcutaneous injections, difficulty attributing adverse effects to the correct agent, additional cost without proven benefit, and potential quality variability in compounded lipotropic products

American Journal of Physiology, 266(6), 21902197

Tang M, Lu X, Zhang C, Du C, Cao L, Hou T

In the near future, scientific communities will provide more data toward all the topics analyzed in this thorough and state-of-the-art critical review article on CRP