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Targeting P62 by sulforaphane promotes autolysosomal degradation of slc7a11, inducing ferroptosis for osteosarcoma treatment

Nature 581, 465469

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4.2.3 ACSL4 inhibitors Glitazones, including TRO, ROSI, and PIO, mitigate ferroptosis by targeting ACSL4, thereby preventing PUFA activation and reducing lipid peroxidation (Kim et al., 2001)
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Reactive oxygen species in vascular wall
