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Histology (H&E), IHC (MUC2 and Nrf2), ROS (ELISA), gene expression (qRT-PCR), and protein levels (Western blotting) were analyzed in colon tissues

Curcumin has amazing inflammation balancing properties

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However, clinical translation faces key challenges such as tumor heterogeneity, drug delivery efficiency, and complex resistance mechanisms

Depending on their subcellular localization and the existence of unique cis-acting regulatory elements in the upstream promoter region, various GPX genes respond differently to environmental stresses

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