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In addition, L-carnitine has a "detoxifying" role in shuttling accumulated intermediates of metabolism out of impaired mitochondria

Acknowledgements We sincerely thank Hua Hua, Anqi Zeng, Li Liu, Weiwei Tian, Ruirui Wang, Lei Zhang, and Junning Zhao for providing guidance and assistance on this paper

doi: 10.1002/path.4357 114 LeiDYuWLiuYJiangYLiXLvJet al

Beyond 28 days, methylcobalamin and methionine degradation accelerates studies show methylcobalamin loses 30% potency within seven days at room temperature, and even under refrigeration, compound integrity declines measurably after four weeks

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