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Direct provision of TMAO into diet has been shown to increase the development of atherosclerosis in animal models, confirming its pro-atherogenic properties 47 , and multiple clinical studies have confirmed that an elevated TMAO level is associated with increased risks for incident major adverse CV events 48

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Wang T, Du Y, Gong Y, Choo KR, Guo Y (2023) Applications of federated learning in mobile health: scoping review

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