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Very common (more than 1 in 10): mild pain, redness, or swelling at injection site usually fades in a day

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This activation reduces HO levels, increases CAT activity, and upregulates transcription of antioxidant genes, including HO-1, which help maintain redox homeostasis 17

GPX4 is also an important enzyme that protects membranes against lipid peroxidation [122]