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It was developed for a once-weekly diabetes therapy and its clinical trials started in 2016, ending in 2017, after which it was approved by the U.S

What the Phase 1 Data Showed Phase 1 Single-Ascending-Dose Study (Coskun et al., 2022) Forty-seven healthy volunteers received single doses

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In patients with hypothyroidism, these gastrointestinal side effects may be more pronounced or may interact with symptoms of their thyroid condition

Researchers also observed improvements in glucose metabolism markers

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