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Further elucidation of the mechanisms that underlie p53 phosphorylation will yield new therapeutic strategies for ferroptosis-induced tumor suppression

Conversely, reducing the glycolytic activity in T cells, such as through inactivation of the glycolytic master regulator HIF-1, promotes a shift in CD8 T cells towards greater reliance on mitochondrial respiration, thereby enhancing their stemness during chronic viral infection [18]

D.AlamN.MitchellW.WongS.YanZ.et al (2020)

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94 , fiy064 (2018)

Until well-designed human clinical trials specifically examine BPC-157 for neuropathy, the compound remains investigational for this application