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AOD-9604, short for Anti-Obesity Drug-9604, is a synthetic analog of the human growth hormones lipolytic (fat-burning) region

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These results directly confirm that excessive NNMT activation suppresses NAD+ synthesis and impairs energy metabolism, while NNMT inhibition effectively reverses this process, establishing NNMT as a negative regulator of energy metabolism

4A are publicly available in the figshare repository, as part of this record: For the rest datasets from all of figures, can be accessed on upon reasonable request, to Dr