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Hyperglycinemia, not associated with defects in glycine catabolism is commonly termed variant nonketotic hyperglycinemia, the most common cause being associated with defects in the biosynthesis of lipoic acid

The ability to stop myostatin from functioning could be useful in conditions like Duchenne muscle dystrophy (DMD) or in people who suffer muscle loss during prolonged immobility

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European Journal of Human Genetics

For instance, the compound CHG demonstrated competitive inhibition of GLO I, and its suberate diamide derivatives showed even stronger inhibitory effects [156]