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The enhanced solubility observed in both the physical mixture (PM) and freeze-dried (FD) formulations, relative to Lid alone, might be attributed to the facilitated formation of the LidAG complex in solution

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PL significantly increased ROS levels and protein glutathionylation with a concomitant elevation in Nrf-2 expression, thus inducing the redox imbalance to kill two human colon cancer cell lines with mutant p53, HT29 and SW620 ( Trigonelline (TRG) is a plant alkaloid in Trigonella foenum-graecum L