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The drug deferiprone has been shown to inhibit ferroptosis by chelating excess iron within the substantia nigra in vivo (52)

Their adverse effects are hypoglycaemia, GIT disturbances, cholestatic jaundice, agranulocytosis, aplastic and hemolytic anemia, generalized hypersensitivity and dermatological reactions [116]

Glucocorticoids and oxidative stress

192,193,194 Red blood cells, or erythrocytes, have been exploited as delivery systems due to the advantages of prolonging the life span of drugs in circulation and preventing drugs from immune clearance for many years

10.1002/mnfr.200700290 Mol Nutr Food Res

Finally, since the overall role of the immune response in PD animal models is still understudied, interactions between pSYN, microglia, astrocytes, the adaptive immune system, and peripheral inflammation need to be explored