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Summary This chapter describes two ancient metabolic pathways common to all cells in the body: glycolysis and the pentose phosphate pathway

Extracellular macrophage migration inhibitory factor (MIF) downregulates adipose hormone-sensitive lipase (HSL) and contributes to obesity

Acknowledgements This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan, Japan Heart Foundation Grant for Research on Hypertension and Metabolism, and a Grant for Research Foundation for Community Medicine

Prescription of immune checkpoint inhibitors (ICIs) is another beneficial cancer treatment regimen, but systemic administration of ICIs causes immune-related side effects