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Aside from perisynaptic glutamate uptake, astrocytes can also sense extracellular glutamate to more readily adapt to their microenvironments through metabotropic glutamate receptors mGluR3 and mGluR5

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According to a study, CXCL14 was the gene that was downregulated the most in PrEC-31 (+CD82) compared to PrEC-31 (CD82), while CXCL14 was highly expressed in (CD82) [223]

Metabolic activation of the potent carcinogen dibenzo[a,l]pyrene by human recombinant cytochromes P450, lung and liver microsomes