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During exercise, skeletal muscle produces BDNF and releases lactate into the bloodstream, which crosses the blood-brain barrier and triggers additional BDNF expression in the brain

Obviously, it is too early to be overly hopeful since it is still necessary to determine the long-term effects of these compounds and properly verify the potential cardiovascular benefits

CrossRef Recent Updates on the Management of Medullary Thyroid Carcinoma Bo Hyun Kim, In Joo Kim Endocrinology and Metabolism.2016

Ma W, Sun Y, Yan R, Zhang P, Shen S, Lu H, et al

Creekmore BC, Watanabe R, Lee EB (2024) Neurodegenerative disease tauopathies

In vertebrates, free amino acids are metabolized in the liver