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Always refer to the specific storage guidelines provided with your compounded prescription , as formulation variations can exist

Methylation issues if you have histamine issues, gut issues and oestrogen excess, then you wont be methylating properly, and methylation is required for many purposes in the body

Absorption Injected free B12 diffuses through the extracellular fluid into nearby capillaries, enters the bloodstream and binds to TCII (transcobalamin II)

Personal or family history of auto-immune disease for instance, thyroid disease, vitiligo, type 1 diabetes, Sjogrens disease (dry mouth and other symptoms), Addisons disease

Folate status: effects on pathways of colorectal carcinogenesis