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The methionine input (in our model) is 40 M/hr, and if the mass leaving via the polyamine pathway (AMD1) is subtracted, the CBS flux is obtained because at steady state, the mass has nowhere else to go

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Wang P, Tao W, Li Q, Ma W, Jia W, Kang Y

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By regulating both the production of serine and glycine, as well as the enzymes that utilize these amino acids, NRF2 may better influence their fate by funneling them into antioxidant response pathways