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In vitro , we validated this increased gene expression via RT-qPCR and observed that BDG increases the global intracellular concentration of glutathione as well as the level of the oxidized glutathione (GSSG) form

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The nuclear-localized pyruvate can serve as a substrate for nuclear-localized pyruvate dehydrogenase (PDH) which generates acetyl-CoA

This compound is synthesized for in-vitro research focusing on lipid metabolism and adipocyte signaling pathways

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