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Methods A systematic literature search was conducted in PubMed and Google Scholar databases until July 2025

Of the 20 healthy controls (HC), 10 (50%) were mixed-breed dogs, and 10 (50%) were purebred, including 2 Maltese, 2 Toy Poodle, and 1 of each Beagle, Chihuahua, Dachshund, German Shepherd, Golden Retriever, and Siberian Husky

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