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10.1038/jcbfm.2013.70 [DOI] [PMC free article] [PubMed] [Google Scholar] Osonoe K., Mori N., Suzuki K., Osonoe M

The most common pathway influencing drug metabolism often involves the induction or inhibition of CYP450 enzymes, resulting in altered drug exposure levels

They have supplemented this formulation to male participants of a clinical trial of this drug for 2 to 5 months at a daily dose of 2 capsules before their semen has taken for IVF and intra-cytoplasmic sperm injection (ICSI)

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February 9, 1991