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References: [1] Seiwerth, S., Milavic, M., Brcic, L., & Sikiric, P

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The fact that this MIC far exceeds the clinical breakpoint by several-fold to tens of folds strongly suggests that the bacterium likely produces drug-inactivating enzymes, such as aminoglycoside-modifying enzymes, which efficiently destroy antibiotic molecules, leading to high-level resistance

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