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These studies focus on molecular mechanisms and assay readouts, not therapeutic use
Targeting p53 presents a substantial risk of off-target effects
Swaminathan M, Kantarjian H, Daver N, Borthakur G , Ohanian M, Kadia T, DiNardo C, Jain N, Estrov Z, Ferrajoli A, Garcia-Manero G, Konopleva M, Andreeff M, Pemmaraju N, Jabbour E, Alvarado Y, Wierda W, Pinsoy MR, Ravandi F, Cortes J
