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Bone marrow suppression is common and potentially affects all cell lines, with megaloblastic anemia being most common

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Activates ERK1/2 and AKT pathways via growth factor receptor upregulation

"Running out" of B12 usually reflects falling serum levels rather than total depletion

Serious vitamin B12 deficiency may result in a low number of red blood cells (anemia), stomach/intestine problems, and permanent nerve damage.Niacinamide (nicotinamide) is a form of vitamin B3 (niacin) and is used to prevent and treat niacin deficiency (pellagra)