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Alcoholic liver disease is the second major worldwide contributor to cirrhosis incidence, accounting for almost one-third of cases (NIDDK 2014a)

This hypothesis might have been corroborated by the observation that the levels of the cleaved forms of caspase-3 and PARP, both proteins which may be associated with programmed cell death, seemed to be reduced after introduction of AHK-Cu

BMC Psychiatry 12 , 225 (2012)

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Genetic variants related to phase I and phase II detoxification of xenobiotic compounds are linked to multiple chemical sensitivity

Specifically, the signaling pathways related to aldosterone synthesis and secretion, PI3K-Akt signaling pathway, ABC transporters, and Metabolic pathways showed significant enrichment of DEGs