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Y2H screens, for example, while allowing for high-throughput analysis of multiple proteins, are missing much of the in vivo context that could be critical for protein interaction, such as post-translational modifications and multi-protein networks

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Studies of microbial colonization in sterile mice have shown that increased platelet reactivity and thrombosis potential were sufficient to be delivered via microbial CutC-dependent TMA/TMAO production in a host (Skye et al., 2018) ( Figure 1D )

Similarly, identifying microbiomes in ME/CFS blood and brain tissue should be prioritised in ME/CFS research (193)

[DOI] [PubMed] [Google Scholar] 23.Mauermann M.L., Staff N.P