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Conclusion Although glutathione is able to coordinate heme bound iron, forming GShematin, the affinity of glutathione for hematin is such that any heme or hematin generated in the cytoplasm will be almost totally bound to glutathione, forming a 1:1 complex

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Mutations in the gene coding for HJV correlate with low hepcidin expression and severe systemic iron overload, known as hemochromatosis (135)

References 1 Endocrinology (OUP)hGH C-terminal fragment AOD-9604: lipid metabolism and -adrenergic pathway insights (preclinical)